Distant Worlds is a little gem of a game by a New Zealand developer and being marketed through Matrix Games.
It is starting to attract a fair amount of attention and I think it will end up being one of the 'must have' strategy titles in the future - like Europa Universalis I guess.
The game has been described as a 'spread-sheet 4X' game because there seems to be screeds of info on all aspects of the game. But don't be put off by that.
The basic premis is that the AI will run all aspects of your empire for you and you can step in an take over something in particular when-ever you want to. So you can micro-manage or not as much as you like. You can't directly make decisions regarding civilian ships such as freighters etc but everything else can be controlled.
Most games require you to make a certain amount of the choices and decisions such as ship building, colony selection, diplomacy, trading etc. But Distant Worlds will handle it all if you want it to. Or you can step in and take over at any point.
I wrote a short AAR and posted it in the Matrix forum if anyone is interested...
Opening Moves AAR